SSC(Sequence, Structure and Conservation)profiler is running on a server at the Computational Biology Lab at the Institute of Molecular Biology and Biotechnology(IMBB), Heraklion, Greece. For more details see the reference denoted below.
SSCprofiler works using human genomic coordinates (version - hg17). By selecting the chromosome number and the start and end nucleotides, it is possible to scan specific genomic regions for miRNA genes. SSCprofiler also provides a link to the full genome tilling array RNA expression map published by Kapranov et al. Science 316, 2007
The Filtering parameters can be defined below. The default parameters are as defined in the human miRNA gene prediction analysis performed in the SSCprofiler paper.
(Please note that this web interface is limited to sequences up to 1kb).
Oulas et al. NAR. 2009 [Epub ahead of print] - Prediction of novel microRNA genes in cancer-associated genomic regions-a combined computational and experimental approach.
For questions, comments and feedback regarding SSCprofiler
please contact Panayiota Poirazi (poirazi[at]dendrites.gr)